Urea treatment in fluid restriction-refractory hyponatraemia
نویسندگان
چکیده
منابع مشابه
Treatment of hyponatraemia by urea decreases risks of brain complications in rats. Brain osmolyte contents analysis.
BACKGROUND Brain damage (myelinolysis) develops in hyponatraemia after a large increase in serum sodium regardless of the currently available methods of correction. However, a preliminary study suggests that treatment of hyponatraemia with urea limits the risks of brain lesions in rats. Benefits of sustained high blood levels of urea and mechanisms of protection remain hypothetical. METHODS I...
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Severe hyponatraemia (serum sodium <130 mmol/1) has become increasingly recognised in recent years as a potential complication of fluid therapy in children,' and at least two children in Northern Ireland have died in recent years as a result. Worldwide, death or neurological morbidity related to this condition has recently been reported in more than 50 children.2 Hyponatraemia has also been rep...
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The treatment of hyponatraemia due to SIADH is not always as straightforward as it seems. Although acute treatment with hypertonic saline and chronic treatment with fluid restriction are well established, both approaches have severe limitations. These limitations are not readily overcome by addition of furosemide, demeclocycline, lithium or urea to the therapy. In theory, vasopressin-receptor a...
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Introduction: In Islamic countries in the month of Holy Ramadan many Muslims based on their religious Legislation refuse fluid intake during the fasting time though instructed to drink after injection of Tc-99m Methylene-diphosphonates [Tc-99m MDP] used for skeletal scintigraphy. We aimed to establish whether fluid restriction in Tc-99m MDP skeletal scintigraphy has an impact on its quality. M...
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ژورنال
عنوان ژورنال: Clinical Endocrinology
سال: 2019
ISSN: 0300-0664
DOI: 10.1111/cen.13930